Brazil and Argentina, along with Uruguay nestled between them, offer several exciting route options for travelers. Here are some suggestions based on popular itineraries:
Route 1: São Paulo – Rio de Janeiro – Iguazu Falls (Brazilian Side) – Iguazu Falls (Argentinian Side) – Buenos Aires – Colonia del Sacramento (Uruguay) – El Calafate (Perito Moreno Glacier National Park) – El Chaltén (Fitz Roy Trek) – Ushuaia (The End of the World + Antarctica) – Buenos Aires
- Duration: 14 days (without Antarctica) or 24–30 days (with Antarctica)
- Entry/Exit Points: Enter through São Paulo, exit from Buenos Aires
- Ideal for:Travelers with limited time who want to cover all the iconic highlights!
This is a streamlined yet classic route that captures the very best of Brazil, Argentina, and Uruguay. In just two weeks, you’ll experience the highlights of all three countries.
Starting in São Paulo, this entry point offers the advantage of affordable flights. After exploring São Paulo and Rio de Janeiro, head to the breathtaking Iguazu Falls. By visiting both the Brazilian and Argentinian sides, you’ll not only enjoy different perspectives of this natural wonder but also have the chance to take thrilling boat rides under the falls—on both sides!
From there, make Buenos Aires your base and take a day trip to Colonia del Sacramento in Uruguay, a UNESCO World Heritage site known for its charming colonial architecture.
Next, venture into the Argentine side of Patagonia. Explore the majestic Perito Moreno Glacier in El Calafate and hike the trails around Mount Fitz Roy in El Chaltén, two of Patagonia’s most iconic experiences. Finally, journey further south to Ushuaia, the world’s southernmost city. For those planning to visit Antarctica, this is where your expedition begins!
This route is perfect for travelers with limited time who want to experience the highlights of all three countries in one incredible trip.
Route 2: São Paulo – Salvador – Rio de Janeiro – Iguazu Falls (Brazilian Side) – Iguazu Falls (Argentinian Side) – Buenos Aires – Colonia del Sacramento (Uruguay) – Córdoba – Mendoza – El Calafate (Perito Moreno Glacier National Park) – El Chaltén (Fitz Roy Trek) – Ushuaia (The End of the World + Antarctica) – Buenos Aires
- Duration: 20 days (without Antarctica) or 30–40 days (with Antarctica)
- Entry/Exit Points: Enter through São Paulo, exit from Buenos Aires
- Ideal for: Travelers who want to explore the classics while immersing themselves in more cultural and diverse experiences.
This route is especially ideal for travelers with a strong interest in cultural experiences. For example, in Brazil, beyond the iconic landmarks, Summer recommends a visit to Salvador, the country’s oldest city and a UNESCO World Heritage Site. Salvador is one of those places where just a glimpse of a photo will make you want to visit—and after you’ve been there, you’ll find yourself reminiscing through your own photos, wanting to return. It’s a city bursting with history, vibrant colors, and a rich Afro-Brazilian heritage that leaves a lasting impression.
The UNESCO World Heritage Site Colonia del Sacramento in Uruguay needs no introduction. Its colonial charm makes it a must-visit. But beyond the famous Colonia, Argentina also offers several destinations beloved by cultural enthusiasts.
For instance, Córdoba is a hidden gem. With its rich Jesuit history, stunning colonial architecture, and youthful energy thanks to its vibrant student population, Córdoba is a city that leaves a deep impression.
Another standout destination is Mendoza, located on the border of Argentina and Chile. This is a paradise for wine lovers. Summer spent an entire day learning the intricacies of winemaking, from grape cultivation to the aging process, all while enjoying wine tastings paired with gourmet meals at local vineyards. Mendoza’s wine estates offer an immersive experience of “eat, drink, and savor,” perfect for indulging in the local culture.
Additionally, Mendoza is well-known among mountaineers as the gateway to Aconcagua, the tallest peak in South America. For anyone planning to conquer this summit, Mendoza is the essential starting point. Whether you’re a wine lover or an adventurer, this region offers something truly special.
Route 3: São Paulo – Rio de Janeiro – Lençóis Maranhenses National Park – Pantanal Wetlands – Bonito – Iguazu Falls (Brazilian Side) – Iguazu Falls (Argentinian Side) – Iberá Wetlands National Park – Buenos Aires – Colonia del Sacramento (Uruguay) – Talampaya National Park – Valdés Peninsula – El Calafate (Perito Moreno Glacier National Park) – El Chaltén (Fitz Roy Trek) – Ushuaia (The End of the World + Antarctica) – Buenos Aires
Duration: 21 days (without Antarctica) or 30–40 days (with Antarctica)
Entry/Exit Points: Enter through São Paulo, exit from Buenos Aires
Ideal for: Travelers who are passionate about breathtaking natural landscapes and wildlife.
When it comes to cultural experiences, how can we forget about natural wonders? In the vast and diverse landscapes of South America, there’s definitely a route for every nature lover!
Take Brazil, for example. The surreal Lençóis Maranhenses National Park, the wildlife paradise of the Pantanal Wetlands, and the rising star Bonito—each is a masterpiece of nature. Every time I recommend a route, I really struggle to leave any of these gems out. After marveling at Iguazu Falls, Summer suggests a hidden gem in Argentina that few people know about: the Iberá Wetlands National Park. When Summer first set foot there, it seemed unremarkable at first glance, but as she ventured deeper, she was utterly blown away. The wildlife, the tranquility, and the raw beauty of this place left her reluctant to leave! For nature enthusiasts looking to go off the beaten path, Iberá is a must-visit.！
Summer also recommends Talampaya National Park in the central plateau of Argentina. Talampaya offers stunning red rock canyons and ancient petroglyphs, making it a true natural wonder.
After Talampaya, head to the Valdés Peninsula along the Atlantic coast. If the timing is suitable for the season, you’ll be able to witness breathtaking wildlife, including whales and penguins. And don’t miss the grand spectacle of orcas stranding themselves on the shore to hunt seals—it’s a nature lover’s dream come true!
And of course, for those who adore nature’s beauty, how could you possibly skip Antarctica? Once you’ve made it to Ushuaia, the southernmost city in the world, visiting Antarctica is as easy as can be. It’s the ultimate destination for anyone wanting to experience the untouched beauty of the White Continent!
For those looking for more route options and combinations in Argentina, Brazil, and Uruguay, reach out to Summer! I’ll help you find the perfect itinerary tailored to your preferences and interest
